I see leopard print as a neutral.
The end.
Okay, let me expand.
When it comes to pattern mixing, leopard is my go-to for pairing (examples: leopard + polka dots, leopard + floral, leopard + stripes, etc.) At this point, I see leopard as black. Straight up.
Leopard is already seen as a 'loud' print so weaving it in with another 'loud' print may be a lot to take in and wear. Starting off with accessories is the best way to ease yourself into the "Leopard as a Neutral" club.
